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Figure 6: Ferrocene (a) and nickelocene (b)

Inflammatory and Cytokine Signaling Genes: In cell culture models of inflammation (e.g., LPS-stimulated macrophages or keratinocytes), GHK-Cu has been investigated for its capacity to suppress the expression of pro-inflammatory cytokines like IL-6 and TNF-

Because astrocytic [Cl ] i is critical for regulating neuronal inhibition, a key question arises: are [Cl ] i shifts merely a byproduct of distinct neuronal activity patterns in different brain states, or do they actively shape neuronal excitability on a state-dependent basis

Recruitment is ongoing and the study is estimated to finish in 2025