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Using the Connectivity Map, a software gene profiling tool developed by the Broad Institute, the researchers identified GHK as a compound which reversed changes in gene expression associated with emphysematous destruction

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10.1093/hmg/ddz250 [DOI] [PMC free article] [PubMed] [Google Scholar] Rose AM, Goncalves T, Cunniffe S, Geiller HEB, Kent T, Shepherd S, Ratnaweera M, OSullivan R, Gibbons R, Clynes D (2023) Induction of the alternative lengthening of telomeres pathway by trapping of proteins on DNA

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