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GSH serves as a primary intracellular antioxidant, and cysteine availability plays a critical role in maintaining GSH levels, as supply of cysteine is the rate-limiting step in GSH synthesis [16, 26]

Earlier detection, improved imaging technologies, minimally invasive interventions, and powerful immunotherapy and targeted therapy combinations have changed the trajectory for many patients

Differential gene regulation in human versus rodent hepatocytes by peroxisome proliferator-activated receptor (PPAR) alpha

formation of double-membrane enclosed vesicles) ( 2 O 2 , but not erastin, STS or rapamycin, was observed ( Using a variation of the modulatory profiling strategy (Wolpaw et al., 2011), the ability of twelve established small molecule cell death inhibitors to prevent ferroptosis in HT-1080, BJeLR and KRAS-mutant Calu-1 non-small cell lung cancer cells was tested