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While all cells can synthesize glutathione for use within the cell, the liver also produces glutathione in larger amounts and exports it into the plasma and bile

2 The potential mechanism of MDR 2.1 Adenosine triphosphate (ATP)-binding cassettes (ABCs) protein family The mechanisms underlying the development of chemotherapy-induced MDR are associated with multiple factors, including genetic and epigenetic alterations, apoptosis resistance, the TME remodeling, and increases in drug efflux and the DNA repair capacity (Roundhill and Burchill, 2012)

Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-ras-harboring cancer cells

Aspirin inhibits glucose-6-phosphate dehydrogenase activity in HCT 116 cells through acetylation: Identification of aspirin-acetylated sites