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Investigated for skin appearance proxies in preclinical and cosmetic-science contexts (texture, firmness, visible tone) without making therapeutic claims

Secondary effects have been documented on mast cells, endothelial cells (blood vessel formation), and the small population of dermal stem cells associated with the hair follicle bulge 1

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Because Epithalon is derived from peptides originally associated with pineal signaling, researchers have examined its influence on circadian-regulated gene expression and endocrine signaling patterns in experimental models