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It is said that you should not have more than one injection every three months as too many injections increase the risk of side effects, such as avascular necrosis, which is the lack of blood flow to a part of the bone that causes it to collapse

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The Translational Gap: From Rodents to Humans Drug development typically moves from animal models to phased human trials

For people with adequate B12 levels, supplementing more does not appear to produce improvements in hair density, growth rate, or thickness