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Ann Intern Med 140:167174 Cupisti A, Farnesi I, Armillotta N, Francesca F (2012) Staghorn cystine stone in a 72-year-old recurrent calcium stone former

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In some embodiments, the compositions comprise a cannabinoid (e.g., CBD) and a cofactor or precursor thereof (e.g., niacinamide) at a molar ratio of between about 1:10 and about 1:55