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NICE guidance recommends at least 150 minutes of moderate-intensity aerobic activity per week, following a Mediterranean-style diet, reducing refined carbohydrates and added sugars, and limiting alcohol consumption in line with UK Chief Medical Officers' guidance

These challenges and pitfalls have been extensively discussed in this review in the sections above covering the topics: Biomarkers, Study design and dietary intake records, Matrices, sampling, clean-up and mass spectrometric analysis as well as Recent trends and challenges in interpretation of human biomonitoring data

However, the research in this area is still in its early stages, and more experimental studies are required to confirm these hypotheses and fully elucidate the complex mechanisms linking cysteine metabolism to AA pathogenesis