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If you want to call it holistic, then use the term to its fullest capacity- not just the whole patient but the entire picture- mind, body, spirit, environment, human/animal bond, and most of all, good old common sense

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(2019) distinguished PD patients who are stable and those with rapid progression, with inconsistent taxa throughout methods and times but uniquely exiting enterotypes, accompanied by a decline in Prevotella for the rapid-progression cases

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