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Jeukendrup AE

Hilar interneurons contain Gamma-amino-butyric acid (GABA) and play a crucial role in maintaining the balance of excitation and inhibition

| 2025 | Curr Rev Musculoskelet Med 3 4Pharmacokinetics of growth hormone-releasing hormone(1-29)-NH2 and stimulation of growth hormone secretion in healthy subjects after intravenous or intranasal administration | Wilton et al

Thats the compensation: an alternate drain the cell can open to offset what you did by inhibiting NNMT, which is part of why nonstop inhibition doesnt necessarily keep delivering the same clean effect forever