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Because angiogenesis is a defining hallmark of tumor growth and metastatic progression, any therapeutic agent that enhances neovascularization could, in theory, facilitate tumor expansion and promote metastatic dissemination

All studies used a range of dosages, from 10 g, 10 ng, 10 pg and 0 .1pg per different body masses (kg/bw) and volumes (mL) BPC 157 in in vitro cultures (Staresinic et al