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PICO, Participant, Intervention, Comparison/Control, and Outcome

Metformin: a review of its metabolic effects

2017 ;24(1) :46-52 Haliloglu S Fibromyalgia in patients with thyroid autoimmunity :prevalence and relationship with disease activity Clin Rheumatol 2017 Jul ;36(7) :1617-1621 Danilov Melatonin in chronic pain syndromes Pain Ther 2016 Jun ;5 :1-17 Favero G Oral supplementation of melatonine protecs against fibromylgia-related skeletal muscle alteration in reserpine-induced myalgia rats Int J Mol Sci 2017 Jun ;18(7) Burgess HJ Morning versus evening brightliht treatment at home to improve function and pain sensitivity for women with fibromyalgia : a pilot study Pain Med 2017 Jan 1 ;18(1) :116-123 2017 2018, Dr

fats are an important energy source during less intense activities where ATP synthesis doesnt have to happen as quickly