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For example, researchers have applied proteomic approaches to identify novel biomarkers, such as plasma sRAGE for detecting presence and progression of emphysema [33], whereas others have adopted metabolomics approaches to identify potential disease severity markers or therapeutic candidates such as purines [8], sphingolipids [2], and glycerol phospholipids [4]

Although the language most typically used in these websites was English, further languages analyzed by NPSfinder included: Dutch, French, German, Italian, Russian, Spanish, Swedish, and Turkish

172 A study in 100 people with neurological symptoms that included dizziness and instability found that 15% of subjects had deficient or borderline low vitamin B12 levels

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