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The Concise Guide to PHARMACOLOGY 2017/18: Ligandgated ion channels

Patients who do not respond adequately to UDCA may be considered for second-line therapies, typically after 1 year, potentially delaying effective treatment for high-risk patients

3B), suggesting that spermine-induced cell death is mediated by acrolein

For example, low plasma glycine concentrations have been consistently linked to type 2 diabetes, obesity and non-alcoholic fatty liver disease (Alves et al