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In Arabidopsis thaliana , low levels of glutathione synthetase have resulted in increased vulnerability to stressors such as heavy metals, toxic organic chemicals, and oxidative stress

The heavy chain 4F2hc is a single transmembrane spanning glycoprotein (also called CD98hc or SLC3A2) 17,18 necessary for correctly trafficking the transporter to the plasma membrane 18,19

Separation of the polar and non-polar fractions was achieved by centrifugation (13,200 g , 15 min)