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Indeed, co-treatment with AZ67, a selective PFKFB3 inhibitor, significantly reversed the enhanced cell death of roxadustat treated neurons exposed to OGD (Figure 8E)

Haemostatic effects of FA-PT-A1 and T17-C6-F7 in thrombocytopenic mice To evaluate haemostatic efficacy we first determined the plasma half-lives of FA-PT-A1 and T17-C6-F7 in mice using sandwich ELISA

Results Compared with the NFD group, body weight, body fat ratio, fasting blood glucose, insulin, homeostasis model assessment of insulin resistance (HOMA-IR), triglyceride, IL-6, serum and liver FFAs including total FFAs, C16:0 and C18:0 were increased in both high fat diet groups and were much higher in the HSF group than those in the LSF group

unsupervised) analysis, the raw UPLC-MS data were processed in Progenesis QI using its Principal Component Analysis (PCA) feature