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Figure 31

Conclusions The publication of the 2024 NICE guidelines on B 12 deficiency represents progress but falls short by proposing to rename pernicious anaemia with autoimmune gastritis. This change does not adequately address the distinct nature of PA as an advanced stage of AIG, characterised by IF deficiency requiring lifelong B 12 treatment

they can indicate that the skin has lost its elasticity or that the sebum production is not being regulated properly

Ferroptosis occurs in immune cells such as macrophages and neutrophils, but its most notable feature is the ability to directly induce death in non-immune structural cells, including osteoblasts, periodontal ligament fibroblasts, and gingival epithelial cells