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However, conventional oral chemotherapy is significantly hindered by multiple physiological, chemical, microbial, and tumor microenvironment-associated barriers within the GIT of CRC patients

[10] This is a textbook example of an inconclusive result being honestly reported rather than overstated

But getting rid of the original condition is always the most important aspect of therapy. Therefore, habit reversal is more of a supplemental treatment to conventional therapies such as topical steroids, internal oral medications, and injectables, rather than a replacement treatment