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Drug Interactions Because these peptides influence vascular, inflammatory, and neurological pathways, interactions with anticoagulants, NSAIDs, immunosuppressants, psychiatric medications, and other pharmaceutical agents are possible but largely unexplored

These combinations lack standardized dosing and introduce variables that complicate research outcomes

Response: We appreciate the commenters' remarks as to the importance of maintaining the ability of the physician/NPP to make changes to a patient's POC outside of the 10-day window, as noted at 410.61(d), if we were to adopt this 10-day window policy

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