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CrossRef Gasdermin D Inhibition Attenuates Mitochondrial Damage and Cardiomyocyte Pyroptosis in Heart Failure with Preserved Ejection Fraction Linlin Chen, Zhiming Jiang, Cheng Li, Hao He, Yulian Yin, Dong Li Molecular and Cellular Biology.2026

Enzymes that use proton transfers to facilitate catalysis, like MnSOD, are expected to undergo changes in protonation states depending on the presence of substrate or product 56,57,58