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This culture method promoted proliferation and enabled propagation of several patient-derived pLGG cells for up to 1 month ex vivo ( 4 In vivo models of pLGG 4.1 Generating non-NF1 pLGG xenograft models for preclinical drug testing One of the ultimate goals for developing pLGG mouse models is for preclinical drug testing

However, the levels of the compound it is made from, L-carnitine, decline with age

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In addition, in terms of the prodrug approach, not all drugs can be conjugated with the promoiety to be recognized as a substrate of the transporter due to the difficulties in synthesis implementation or limits of the chemical structures of the compounds