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Niacinamide also contributes to supporting skin clarity and smoothness, while Glutathione and Vitamin C help enhance the appearance of radiant skin and resist the look of dullness caused by external factors

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Furthermore, a subset of patients demonstrates suboptimal responses to first-line treatments such as metformin, highlighting the need for personalized therapeutic strategies (10)

Variation in vasomotor and neuronally-mediated symptoms of menopause genetic considerations Menopausal symptoms are reported in populations of women from around the world (Freeman and Sherif, 2007)