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Vitamin B12, also known as cobalamin, is essential for various bodily functions, including red blood cell production, releasing energy from food, and maintaining nervous system health

Both the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) have issued strict guidelines for immunogenicity assessment, which are highly relevant to the development of peptide-based alopecia treatments [124]

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In response to the inflammatory mediator, the atherosclerosis lesion may be heavily infiltrated with pro-inflammation cells, including macrophages, T cells and neutrophils (49), and the lesion size began to enlarge (50)